By The Associated Press

Today is Tuesday, April 21, the 112th day of 2020. There are 254 days left in the year.

Today’s Highlight in History:

On April 21, 1976, clinical trials of the swine flu vaccine began in Washington, D.C.

On this date:

In 1509, England’s King Henry VII died; he was succeeded by his 17-year-old son, Henry VIII.

In 1789, John Adams was sworn in as the first vice president of the United States.

In 1816, Charlotte Bronte, author of “Jane Eyre,” was born in Thornton, England.

In 1836, an army of Texans led by Sam Houston defeated the Mexicans at San Jacinto, assuring Texas independence.

In 1910, author Samuel Langhorne Clemens, better known as Mark Twain, died in Redding, Connecticut, at age 74.

In 1918, Manfred von Richthofen, 25, the German ace known as the “Red Baron” who was believed to have downed 80 enemy aircraft during World War I, was himself shot down and killed while in action over France.

In 1926, Britain’s Queen Elizabeth II was born in Mayfair, London; she was the first child of The Duke and Duchess of York, who later became King George VI and the Queen Mother.

In 1930, fire broke out inside the overcrowded Ohio Penitentiary in Columbus, killing 332 inmates.