Neighbors help to return a giant figure of the "Santa Muerte," or Death Saint, to a home, after it was displayed in the street to celebrate the saint's monthly festival day, which drew thousands of devotees despite the ongoing coronavirus pandemic, in Mexico City's Tepito neighborhood, Monday, June 1, 2020. Despite the ongoing coronavirus pandemic, thousands of devotees, few wearing face masks amidst the dense crowd, made the monthly pilgrimage Monday to pray or give thanks to Santa Muerte, one of several unofficial folk saints worshipped in Mexico. (AP Photo/Rebecca Blackwell)

WELLINGTON, New Zealand (AP) — South American countries at the epicenter of the coronavirus pandemic are choosing to reopen even as case numbers rise, ignoring the example set by Europe in which nations waited for the worst to pass.

Meanwhile in the U.S., there are concerns that widespread protests over the death of George Floyd, a black man pinned at the neck by a white police officer, could cause new outbreaks in a nation where the virus has disproportionately affected racial minorities.

And a new estimate by the Congressional Budget Office cautioned the damage to the world’s largest economy could amount to nearly $16 trillion over the next decade if Congress doesn’t work to mitigate the fallout.

Experts are concerned about what’s happening in South America.

“Clearly the situation in many South American countries is far from stable. There is a rapid increase in cases, and those systems are coming under increasing pressure,” said Mike Ryan, the executive director of the World Health Organization’s emergencies program.

His warning came as some of Brazil’s hardest-hit cities, including the jungle metropolis Manaus and coastal Rio de Janeiro, were starting to allow more activity. Brazil has reported more than 526,000 cases of the virus, second only to the 1.8 million reported by the U.S.

Elsewhere in the region, Bolivia’s government has authorized reopening most of the country, while Venezuela has unwound restrictions. Ecuador’s airports are resuming flights and shoppers are returning to some of Colombia’s malls.

Further north in Mexico, President Andrés Manuel López Obrador kicked off the nation’s return to a “new normal” Monday with his first road trip in two months as the nation began to gradually ease some of its virus restrictions.

López Obrador said he’s taking all necessary precautions — he drove the 1,000 miles from Mexico City over the weekend rather than flying — on a trip to promote construction of the Mayan Train, one of his signature infrastructure projects.

In South Korea, new cases ticked up today. Areas around Seoul moved to curb large gatherings and officials urged churchgoers and some health care workers to avoid crowds.

The U.S. Congressional Budget Office issued a new estimate that said that over the decade ending in 2030, total GDP output could be $15.7 trillion lower than it had been projecting as recently as January. That would equal 5.3% of lost GDP over the coming decade.

After adjusting for inflation, the CBO said the lost output would total $7.9 trillion, a loss of 3% of inflation-adjusted GDP.

The CBO called this a “significant markdown” in GDP output as a result of the pandemic.

“Business closures and social distancing measures are expected to curtail consumer spending, while the recent drop in energy prices is projected to severely reduce U.S. investment in the energy sector,” CBO Director Philip Swagel said in a letter.

In the U.S., at least a quarter of COVID-19 deaths were among nursing home residents, a new report said.

The report, prepared for U.S. governors, said nearly 26,000 nursing home residents have died from the virus — a number that is only partial and likely to go higher.

The Centers for Medicare and Medicaid Services and the Centers for Disease Control and Prevention reported 60,000 cases of coronavirus illness among nursing home residents, according to a copy of a letter addressed to the governors and an accompanying chart provided to The Associated Press.

The data was based on reports received from about 80% of the nation’s 15,400 nursing homes as of May 24. But some states with high rates of nursing home deaths appeared to have low levels of response to the survey, intended as a first step toward developing policy changes.