Novak Djokovic puts his hand on his heart after defeating Rafael Nadal in their semifinal match of the French Open on Friday in Paris. (AP photo)

PARIS — Sprinting, sliding and stretching, anticipating each other’s moves for four sets and more than four hours, Novak Djokovic and Rafael Nadal produced a masterpiece in the French Open semifinals.

Djokovic, as it happens, is one of only two men in tennis history who knows what it takes to beat Nadal at Roland Garros. And now Djokovic has done it twice — this time ending Nadal’s bid for a 14th championship there and record-breaking 21st Grand Slam title overall by coming back to win their 58th career matchup 3-6, 6-3, 7-6 (4), 6-2 on Friday night.

“Just one of these nights and matches that you will remember forever,” said the top-seeded Djokovic, who trailed 2-0 in the closing set before reeling off the last half-dozen games to reach his sixth final at the clay-court major tournament.

“Definitely the best match that I was part of ever in Roland Garros, for me, and (one of the) top-three matches that I ever played in my entire career — considering quality of tennis, playing my biggest rival on the court where he has had so much success and has been the dominant force in the last 15-plus years,” Djokovic said, “and the atmosphere, which was completely electric.”

It was Nadal’s third loss in 108 matches at a tournament he won each of the last four years, including by beating Djokovic in the 2020 final.

Nadal’s first defeat at the French Open came against Robin Soderling in 2009; the next against Djokovic in 2015.

And to think: There wasn’t even a trophy at stake in this one. That will happen Sunday, when Djokovic, a 34-year-old from Serbia, faces Stefanos Tsitsipas, a 22-year-old from Greece.

The fifth-seeded Tsitsipas edged sixth-seeded Alexander Zverev 6-3, 6-3, 4-6, 4-6, 6-3 earlier Friday.